Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

1 Department of Science and High Technology, University of Insubria, Como, Italy 2 Center of Neuroscience Research, University of Insubria, Busto Arsizio, Italy Introduction: i-Motifs (iMs) are ...

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ABSTRACT: The absence of the atp8 gene in the mitochondrial genomes of Platyhelminthes and certain other mollusks has garnered significant attention in recent years. Growing evidence suggests that ...

ABSTRACT: Genomic surveillance has proven to be a critical source of information for understanding and responding to the COVID-19 pandemic. In Africa, genomic surveillance was very limited, and few ...

Aligning large language models (LLMs) with human values remains difficult due to unclear goals, weak training signals, and the complexity of human intent. Direct Alignment Algorithms (DAAs) offer a ...

I hope this email finds you well. My name is Xueqin Wang, and I am currently using your tool SpruceUp for processing multiple sequence alignment data. First, I want to express my appreciation for this ...

There were seven confirmed algorithm updates (two less than last year). But Google's March core update was Google's biggest update ever. Google launched seven official and confirmed algorithmic ...