在湿式实验室验证中，DrugCLIP实现了15%的去甲肾上腺素转运蛋白命中率，并且在与靶蛋白的复合物中确定了两种已鉴定抑制剂的结构。对于甲状腺激素受体相互作用因子12，一种缺乏全结构和小分子结合物的靶标，DrugCLIP仅使用AlphaFold2预测结构就达到了17.5%的命中率。最后，研究人员发布了GenomeScreenDB，这是一个开放的数据库，提供了针对5亿种化合物筛选的约10，000种人 ...

Science in the United States has never been stronger by most measures. Over the past five years, the nation has won more scientific Nobel prizes than the rest of the world combined — in line with its ...

Research by philosopher of science and Honorary Research Associate at Bangor University, Byron Hyde, looked at the role of transparency in fostering public trust in science. Hyde argues that, to find ...

The reporters analyzed 35 years of grants funded by the National Science Foundation. The National Science Foundation, which funds much of the fundamental scientific research at American universities, ...

In five years of writing for various audiences, Uche has learned to simplify career-focused content for ambitious learners regardless of their qualifications. Her work is published in notable ...

“By amplifying human intelligence, AI may cause a new Renaissance, perhaps a new phase of the Enlightenment,” Yann LeCun, one of the godfathers of modern artificial intelligence (AI), suggested ...

We explain the administration’s cuts to research. By Alan Burdick I’m an editor and occasional reporter of health and science news. Late yesterday, Sethuraman Panchanathan, whom President Trump hired ...