As compared with BA.2, the BA.2.12.1 subvariant has substitutions L452Q and S704L in its spike protein, and both BA.4 and BA.5 have additional changes. Substitutions L452Q, L452R, and F486V are in the ...
Panel A shows the lineage of mutations that have been identified in the omicron BA.1, BA.2, BA.2.12.1, and BA.4 or BA.5 subvariants of SARS-CoV-2, as compared with the reference WA1/2020 isolate. BA.4 ...
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