Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical ...

Top: Random Illumination Microscopy (RIM) utilizes random speckle patterns to achieve super-resolution imaging of biological tissues, improving resolution by a factor of two compared to the optical ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

A project at the University of Strathclyde has now shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical components that enable super-resolution ...

Overcoming the resolution limit in a light microscope of around half a wavelength of light (about 250 nanometers) is one of the most significant developments in optics. Due to the wave nature of light ...

Researchers used consumer-grade 3D printers to create sub-$1 optical lenses that enable super-resolution nanoscale biological ...