A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate, becoming essentially a zombie cell.

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

Selective ASO-based JAK2 inhibitor for the treatment of hematological malignancies with JAK2 V617F mutation burden. Use of causal modeling to uncover cell-cell communication dynamics in the tumor ...

Metacaspases, ancestral homologues of the caspase family, are pivotal cysteine proteases found in a wide range of unicellular organisms, including yeasts, algae, and phytoplankton. These enzymes ...

In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis or “cell suicide.” This process is essential for maintaining the body’s balance. When aged ...

Discover the challenges of acute myeloid leukaemia linked to inflammatory cell death and the quest for effective therapies.

Even in death, cells leave a trace. Scientists have discovered a microscopic “Footprint of Death” that not only helps the immune system clean up but can also give viruses a new way to spread infection ...