Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

By Vijay Kumar Malesu New mouse data reveal that ageing neurons struggle to clear synaptic proteins, shifting the burden to ...

Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells—a process called "proteostasis," or protein homeostasis. Brain cells in particular fall prey to ...