Protocadherins, a subfamily within the cadherin superfamily, are fundamental to the precise organisation of neural circuits. They contribute to cell adhesion mechanisms that underlie synaptic ...

Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the ...

Cell adhesion molecule L1, a key member of the immunoglobulin superfamily, plays a pivotal role in the development and maintenance of the nervous system. Its functions extend from guiding neuronal ...

Researchers identified DMTF1 as a key transcription factor driving neural stem cell regeneration during aging. The study ...

Researchers from the lab of Richard Simerly have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. The work also suggests a novel role for the hunger ...

Axons from AgRP neurons, in red, innervate oxytocin neurons, in green, in the PVH. Neuronal activity of AgRP neurons is required for normal targeting of their axons to oxytocin neurons, as well as for ...

A genome-wide CRISPR study maps 331 genes essential for early brain development, identifying PEDS1 as a new ...

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" ...

How does our brain, which is capable of generating complex thoughts, actions and even self-reflection, grow out of essentially nothing? An experiment in tadpoles, in which an electronic implant was ...

Early brain development is a biological black box. While scientists have devised multiple ways to record electrical signals in adult brains, these techniques don’t work for embryos. A team at Harvard ...

Find out how stainless steel neural probes reduce brain damage risks while enabling safer, deeper, and more reliable neural ...