Doubly uniparental inheritance (DUI) of mitochondrial DNA (mtDNA) represents a rare and intriguing deviation from the standard model of strictly maternal inheritance. In bivalves, DUI manifests as the ...

Recent research has shed light on the complex processes that cells use to maintain the quality of mitochondrial DNA (mtDNA) for inheritance across generations. These processes are particularly ...

Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

In a groundbreaking UK first, eight healthy babies have been born using an IVF technique that includes DNA from three people—two parents and a female donor. The process, known as pronuclear transfer, ...

The UK's pioneering licensed IVF technique to reduce the risk of mitochondrial diseases carried out in Newcastle has seen eight babies born, research shows. All eight babies show no signs of having ...