Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

It has been known in biology for a long time that the excited oxygen molecule singlet oxygen is the main cause of aging in cells. To counter this, nature uses an enzyme called superoxide dismutase to ...

A new technique could make it easier to target and inhibit specific enzymes and other proteins in cells and to turn that regulation on and off at will with light. The approach provides researchers ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely ...

Just because an enzyme has an active site doesn’t mean the rest of the enzyme should be disregarded, as though it were so much dead weight. It influences enzyme function, if only by keeping the enzyme ...

Ensemble map of protein structure. The team’s approach integrates different NMR data to create a map of how different parts of a molecular structure move. Tokyo, Japan – Researchers from Tokyo ...

Explore the role of the cPLA2 enzyme in brain inflammation related to Alzheimer’s disease and its potential as a therapeutic target.

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Scientists have discovered a new function in a plant enzyme that could inspire the design of new chemical catalysts. The enzyme catalyzes, or initiates, one of the cornerstone chemical reactions ...