New findings offer insight into why some embryos fail to develop past zygotic genome activation (ZGA), pointing to an unexpected root of human infertility. A critical point in early development is ...

New findings offer insight into why some embryos fail to develop past zygotic genome activation (ZGA), pointing to an unexpected root of human ...

Integrated screening and CRISPR reveal eleven previously unknown factors essential for early embryo development. They showed ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...

A new study using stem cell-based models has shed new light on how the human embryo begins to develop, which could one day benefit the development of fertility treatment. The study led by at the ...

A critical transition in early human development is regulated not by our own genes, but by DNA elements called transposons that can move around the genome, Sinai Health researchers have found. This ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

In A Nutshell Egg geometry drives development: The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller cells at the margin—a size ...