A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at ...

QUICK FIX: From left, Frederick Alt and Guillermo Taccioli and their colleagues identified DNA-dependent kinase as a key enzyme involved in DNA repair. The way that DNA repairs itself recently has ...

USC Dornsife researchers discover that “condensates” formed by the protein Nup98 help cells avoid catastrophic errors when repairing breaks in tightly packed DNA, a finding with implications for ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...

New study shows that in women with BRCA1 or BRCA2 mutations, their breast cells already carry a clear pattern of DNA “damage ...

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...