A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

When people think of DNA, they visualize a string-like double helix structure. In reality, the DNA double helix in cells is supercoiled and constrained into loops. This supercoiling and looping are ...

A team of physicists working at the intersection of theory and experiment are shedding new light on the 'teamwork' of molecular motors -- called RNA polymerases (RNAPs) -- that mediate DNA ...

Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...

An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA’s shape have an important influence on gene activity and energy production.

Histone proteins at the core of nucleosomes and their tails exert control over the exposure of genes for binding, as demonstrated in simulations researchers. The protein complex that holds strands of ...

The expression pattern of a single gene or multiple genes can be investigated using a technique RNA microarray. In this technique, RNA molecules are ‘spotted’ onto a solid surface. These act as probes ...

A groundbreaking new study from Bar-Ilan University shows that one of sleep’s core functions originated hundreds of millions of years ago in jellyfish and sea anemones, among the earliest creatures ...