Although continuous flow chemistry—wherein molecules are made in a continuous process rather than in batches—has gained ground in academic labs, its adoption by industry and contract manufacturing ...
The antibiotic cefazolin is an essential drug according to the World Health Organization (WHO). It is usually produced via batch manufacturing, but this multistep process is time-consuming, wasteful ...
Continuous pharmaceutical manufacturing represents a significant shift from traditional batch processing, integrating continuous flow methods, advanced process analytical technology (PAT) and ...
Aim: To demonstrate the potential of in-line nanoparticle size measurements using the NanoFlowSizer (NFS) as a PAT method. To achieve real-time process control by establishing automated regulation of ...
The continuous casting process is a pivotal industrial technique in the manufacturing of steel, enabling cost‐effective production by solidifying molten metal into semi-finished billets, blooms, or ...
People have recognized the promise of continuous manufacturing processes ever since Henry Ford’s auto assembly line kicked into action. Even so, pharmaceuticals are still made in batches. Proponents ...
Continuous manufacturing offers advantages in both biotherapeutic and API manufacturing but still poses challenges. The forward movement of the bio/pharmaceutical industry is driven by fast-paced ...
Researchers at pharmaceutical giant Eli Lilly have developed a continuous manufacturing process for a chemotherapy drug, officials with the company recently announced. In their paper published in the ...
The size and size distribution of nanomedicines in various (bio)pharmaceutical products, including liposomes, lipid nanoparticles, recombinant proteins, and antibodies, plays a significant role in ...
Most facilities that fail in lean implementations have weak quality systems. More specifically, they have failed to create stable process flow. If you have some or even one of these issues, you will ...