This method combines the CRISPR-Cas9 technique with the Single-Strand Annealing (SSA) repair pathway, enabling genome-wide changes to be carried out more efficiently and without leaving unwanted scars ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far safer and more flexible. Instead of cutting DNA, the new approach scrubs away ...

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that ...

If genetic editing wasn't crazy enough for your reality, a recent breakthrough in CRISPR(Opens in a new window) technology has paved the way for editing entire gene networks in a single step. While ...

CAR-T cells are highly effective in treating selected blood cancers. However, challenges remain with this new therapy, which was first approved in 2017 in the USA and a year later in Europe for ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and ...

(a) Utilizing HCR and CRISPR-Cas12a double amplification technique, a highly sensitive apta-HCR-CRISPR method was devised for the detection of TEV protein. (b) A novel CRISPR-Cas12a/Cas13a approach, ...

CRISPRgenee is a new method that combines gene silencing and cutting to improve loss-of-function studies in human cells. (Nanowerk News) The 2020 Nobel Prize in Chemistry was awarded for the ...

On the left: poplar sprouts containing CRSPR-edited gene. On the right, poplar sprouts with the same CRSPR edit plus gene enhancements to improve growth. Credit: UMD Ten years ago, a new technology ...

Liquid biopsy is increasingly recognized as a promising tool for cancer detection and treatment monitoring, yet its effectiveness is often limited by the extremely low levels of tumor-derived DNA ...